Neptune Krill Oil Better than Fish Oil for Lowering Cholesterol


white bottle pouring out red neptune krill oil pills for cholesterol

A recent study shows patients taking 500 mg. of Neptune kill oil per day lowered elevated cholesterol levels up to 19% and was more effective than fish oil.

The study published in the 2004 issue of Alternative Medicine Review concluded that 1 – 3 grams a day of Neptune krill oil was more effective at reducing total cholesterol, triglycerides, glucose, LDL and HDL, compared to both fish oils and a placebo.

Below is a summary the actual study results:

Montreal, Canada – Researchers took a group of one hundred and twenty (120) patients and randomly assigned them to 4 groups.

Each group received either krill oil (2 different dosages), fish oil or a placebo.

  • Group 1 – took 0.5 – 1.5 grams/day of Neptune Krill Oil (NKO)
  • Group 2 – received 2 – 3 grams/day of Neptune Krill Oil 
  • Group 3 – received Fish Oil (FO) containing 180 mg of EPA (eicosapentaenoic acid) and 120 mg of DHA (docosahexaenoic acid) at 3 grams/day
  • Group 4 – received a placebo of crystalline cellulose

The Neptune Krill Oil and cholesterol study lasted for 3 months.

Primary parameters tested at baseline and 90 days were:

  • Total Blood Cholesterol
  • Triglycerides
  • LDL cholesterol
  • HDL cholesterol
  • Glucose


Results of Neptune Krill Oil and Cholesterol Study


1. Patients taking 3 grams/day of Fish Oils:

  • Total cholesterol dropped by 6%
  • LDL (unhealthy cholesterol) decreased by 4%
  • HDL (healthy cholesterol) increased by 4%

These results confirmed earlier reports that fish oils may help lower cholesterol and improve blood lipids.

However, researchers found that Neptune Krill Oil was more effective for the management of hyperlipidemia by significantly reducing total cholesterol, LDL and  triglycerides and increasing HDL levels.

2. Patients taking 500 mg/day of Neptune Krill Oil:

  • Total cholesterol decreased by 19%
  • LDL decreased by 44%
  • HDL increased by 33%

Researchers learned that a single 500 mg dose of Neptune krill oil resulted in a 300% improvement in cholesterol compared to fish oils; and there was also a substantial difference in the LDL and HDL cholesterol levels.

3. Patients taking 3 grams/day of Neptune Krill Oil also experienced similar results:

  • Total cholesterol decreased by 18%
  • LDL decreased by 39%
  • HDL increased by 60%

The researchers discovered that increasing the dosage of Neptune krill oils by almost 6 times (to 3 grams a day) also produced an effective reduction on high cholesterol blood levels.


Summary of Neptune Krill Oil and Cholesterol Study:

This study appears to indicate that Neptune krill oil is almost 3 times more effective than using a standard fish oil to lower elevated cholesterol levels.

Researchers were not able to explain why krill oil was more effective than fish oils for lowering cholesterol, but they did state:

“The exact mechanism of action for krill oil’s lipid-lowering effects is not yet entirely clear. However, krill oil’s unique biomolecular profile of omega-3 (EPA/DHA) fatty acids already incorporated into phospholipids has exhibited a lipid lowering effect on the level of the small intestine, which distinguishes krill oil from other known lipid-lowering principals.”

Neptune krill oils appear to be an effective treatment for enhancing cardiovascular health in individuals with elevated cholesterol levels. 

While additional research is needed to assess for any potential long-term health benefits, krill oils appear to offer the following:

  • May lower elevated cholesterol levels
  • Can reduce LDL (unhealthy cholesterol)
  • Appears to lower high triglyceride levels
  • Increases HDL (healthy cholesterol)
  • May be more effective than fish oils for managing high lipid levels in the blood.
  • Surpasses fish oils for a greater reduction in LDL (the bad cholesterol).
  • A lower dose of 500 mg. krill oil appeared to offer more noticeable health benefits compared to fish oils and placebo.

The exact brand of krill oil used in this cholesterol study is called Neptune Krill Oil.

These types of natural health products can be purchased at most health food stores or online retailers.

It’s recommended you consult with your physician before considering using this product.

Research References:

Alternative Medicine Review. 2004 Dec;9(4):420-8. Evaluation of the effects of Neptune Krill Oil on the clinical course of hyperlipidemia. Bunea R, El Farrah K, Deutsch L. Department of Internal Medicine, McGill University, Montreal, Quebec, Canada.

Influence of the physicochemical form of polyunsaturated fatty acids on their in vivo bioavailability;  Cansell M, Moussaoui N, Denizot A, Combe N. 94th Annual AOCS Meeting & Expo PHO1: Phospholipids for Improving Bioavailability Chair: Michael Schneider, Consultant, Germany.


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Author Details
Author Details
Kevin is a full-time blogger with a passion for functional, whole food nutrition. A former Registered Respiratory Therapist with over 25 years experience in Intensive Care and Emergency Medicine, he also has additional training as a Certified Natural Products Advisor. He enjoys a vibrant lifestyle that includes healthy foods, workouts focusing on core strength with flexibility and longboarding to stay fit and agile.