Hi Pam, I think it could be possible to spray Oil of Oregano on mites, however you may not want to spray it on your mattress as the fabric may absorb the strong smell of oregano oil. I think it's better to spray Oil of Oregano on hard contact surfaces or areas where you're not concerned about the scent of oregano oil lingering. You may have to replace your mattress if the mites have already infested the inner areas of it.

For internal use of Oil of Oregano I like to use sublingual administration (placing a few drops under the tongue and letting it get absorbed by the mucous membranes). Another method of taking Oil of Oregano is placing a few drops in a glass of water and then drinking the water. I may also take Oil of Oregano a few times a day throughout the day to treat more stubborn cases.

Best way to take oil of oregano internally is to put drops in a capsule (one that you can take apart. woorm wood was just right for me and I actually rid the mites, eggs, and nymps by using this method; A nathuralpathic Dr. told me to do this; I had be self medicating for 6 months and now relief. Mites and all the cycle hate this oil worst than anything else I had tried.