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Flaxseed oil and Cancer


Flaxseed oil and cancer - Can you use flaxseed oil to prevent or reduce your risk for cancer?

Flaxseed and its oil are a plant-source of the omega 3 fatty acid, alpha linolenic acid. Why would you want to take this healthy fat? Well, some of the health benefits of omega 3 fatty acids are fighting inflammation, boosting the immune system, reducing blood clots and improving your mood.

With benefits like these, researchers are investigating if flaxseed and flaxseed oil can play a role in fighting cancer, or reducing your risk for it. There are limited studies done on human subjects, but the results of these animal tests look promising.

First, we'll look at the research on ground flaxseeds, followed by flaxseed oil.



1. Ground Flaxseeds and Cancer

flax seeds

Researchers in Toronto, Canada discovered when rats ate a flaxseed diet they reduced certain types of genetic damage up to 30%.

Another study from South Dakota had rats eat corn meal or flaxseed diets. Scientists compared the incidence of colon tumors and tumor size in both diets. Researchers found the flaxseed diet reduced the appearance of colon tumors from 83% down to 29% and the tumors shrank from 44 mm. down to 5 mm.


Breast Cancer and Ground Flaxseed Study

ground flaxseeds muffin for breast cancer

Here's an interesting study looking at ground flaxseeds and breast cancer.

Researchers at the University of Toronto gave breast cancer patients, awaiting treatment, muffins with 25 grams of ground flaxseeds. Another group of women who were also awaiting treatment were given muffins without flaxseeds.

The results were: Women who received the flaxseed muffins showed slower growing tumors. There was no change in the size or growth of the tumors in women who didn’t get the flaxseed muffins.



2. Flaxseed Oil and Cancer

What about using flaxseed oil on cancer? Can this oil be used to help prevent certain types of cancer?

Researchers at The Department of Nutritional Sciences at University of Toronto conducted an experiment to see if a corn meal, flaxseed or flaxseed oil diet would have any effect on rats with cancer.

The test subjects were divided into 3 groups and given one of the three diets for 7 weeks. The rats eating flaxseed and flaxseed oil displayed an average tumor volume over 50% smaller than rats eating the corn meal diet. The group eating flaxseeds had the lowest amount of new tumor growth.

Doctors believe this effect is due to the lignans found in the hull of ground flaxseeds.


Side Note

Lignans are phyto-estrogens (a plant-like estrogen) and an antioxidant.

The main flaxseed lignan is called secoisolariciresinol diglucoside (SDG), found in the hull. Flaxseed oil has small amounts of lignans.

According to research, you need a minimum of 50 mg. of SDG per day to benefit from these healthful ingredients.

The Flax Council of Canada says one rounded table-spoon of ground flaxseed can contain 50 mg. to 150 mg. of lignans. Want to learn more about lignans?

Check out the Flax Lignan Information Bureau for more info on how you can benefit from flaxseed lignans.




Flaxseed Oil and Cancer of the Colon

What effect does flaxseed oil have on colon cancer? Scientists at the Department of Pharmaceutical Sciences in South Dakota took a group of rats and put colon tumor cells into them.

They fed one group of rats corn oil and the other group received flaxseed oil. The rats on the flaxseed oil diet had a 50% decrease in the appearance of new tumors and the rats fed corn oil displayed larger tumors.



Editorial Comments on Flaxseed Oil and Cancer:

While research in limited in this area, there are some promising results from the available studies.

The test results from using flaxseed oil on cancer cells looks promising; as does the study of ground flaxseed muffins and reduced incidence of breast cancer. However, more human studies are needed before any definite conclusions can be made.

Flaxseeds are an excellent source of omega 3 fatty acids, fiber and lignans. These ingredients will support healthy immune function, provide antioxidant protection and fight inflammation. Flaxseeds and flax seed oil aren't a magic cure, but they can play an important part in maintaining a healthy lifestyle.



Research References:

The influence of dietary flaxseed and other grains, fruits and vegetables on the frequency of spontaneous chromosomal damage in mice. Mutation Research. 2004 Jul 13;551(1-2):213-22. :

Chemopreventive effects of dietary flaxseed on colon tumor development Nutrition and Cancer 2006;54(2):216-22. Bommareddy A, Arasada BL, Mathees DP, Dwivedi C. Department of Pharmaceutial Sciences, South Dakota State University, Brookings, SD 57007, USA.

Flaxseed oil and Cancer Research: Flaxseed and its lignan and oil components reduce mammary tumor growth at a late stage of carcinogenesis. Carcinogenesis, 1996 Jun;17(6):1373-6 Thompson LU, Rickard SE, Orcheson LJ, Seidl MM. Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Ontario, Canada.

Chemopreventive effects of dietary flaxseed oil on colon tumor development. Nutrition and Cancer. 2005;51(1):52-8. Dwivedi C, Natarajan K, Matthees DP. Department of Pharmaceutical Sciences, South Dakota State University, Brookings, SD 57007, USA.

The inhibitory effect of flaxseed on the growth and metastasis of estrogen receptor negative human breast cancer xenograftsis attributed to both its lignan and oil components. International Journal of Cancer. 2005 Sep 20;116(5):793-8 Wang L, Chen J, Thompson LU. Department of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

Flaxseed oil and Cancer Research: Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer. Clinical Cancer Research. 2005 May 15;11(10):3828-35 Thompson LU, Chen JM, Li T, Strasser-Weippl K, Goss PE. Department of Nutritional Sciences, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada.



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