Researchers found 100 mcg/kg. of carvacrol caused a decrease in heart rate, mean arterial pressure, and diastolic and systolic pressures in anesthetized rats.
The study didn't indicate how much the pressures decreased.
Of course rats are different than humans. But if we convert this to humans, this dosage is equivalent to a 70 kg. person taking almost 7 grams of carvacrol.
Depending on the brand of oregano oil, 4 drops of oil will yield about 13 mg. of carvacrol and a 150 mg. softgel may contain up to 7 mg. of carvacrol.
Researchers found no effects on blood pressure at dosages of 1, 10 and 20 mcg/kg in animal studies.
It appears that taking excessively high dosages of Oil of Oregano may cause a decrease in blood pressures, but there are no documented human studies to prove this.
To be safe, consult you healthcare provider when using any nutritional supplement and don't exceed the recommended dosages suggested by the manufacturer.
Kevin L.
Sep 26, 2008 Rating
Oil of Oregano & blood pressure - my personal experience by: Anonymous
I am not a scientist, and I am new to using herbal remedies, but I have high blood pressure that is currently controlled with medication. I started taking Oil of Oregano a week ago, and my first dosage sent my BP through the roof. I had a screaming headache for almost two days. However, I continued using the O of O, and there are no signs of side effects now. I no longer get any headaches, and actually, I feel great! It has been one week now. I do think there is something there that can affect folks with hypertensive tendencies initially, but from my own experience, it seems to go away after a couple of days.
Again, I'm no scientist. Just my own .02 cents. Good luck!
Sep 27, 2008 Rating
re: Oil of Oregano & blood pressure - my personal experience by: Anonymous
Thanks for sharing your experiences with us. Can you tell us what brand of Oil of Oregano you were using and the dosage taken? It's interesting that Oregano Oil initially caused an increase in your blood pressure and then it regulated itself. I'm sure other readers would be interested to know if this was dependent on the dosage taken or if others could expect this possible side effect.
Kevin L.
Oct 30, 2008 Rating
Oil of Oregano and Blood Pressure by: Anonymous
I was using a local store brand with a minimum of 70% (or 30mg) per 43 mg of Oil of Oregano. I was taking 4 drops about 3 times per day, diluted in water or tea or juice.
Like I said, it cleared up after the initial two days, and has not come back and I still take it daily.
Dec 15, 2008 Rating
Blood pressure and Oil of Oregano by: Anonymous
I used North American brand and it shot my pressure to 144/103. The bottom number scared me. The first day was one drop, it cleared a post nasal drip for me. The second day I took about 5 to 7 drops spread out over the day. The third and fourth day about 5 drops spread out. The third and fourth day are when the blood pressure rose significantly. I usually read 122/80 to 135/90. I immediately stopped taking it and my pressure is back down but the 'ball' in my throat where nasal drip accumulates is back!
Dec 20, 2008 Rating
re: Blood pressure and Oil of Oregano by: Kevin
It was wise to discontinue taking Oil of Oregano once you started experiencing high blood pressure. It looks like the higher dosage of 5 drops per day was too much for you - but you did say the initial one drop per day cleared your post nasal drip?
I guess too much of a good thing can have the opposite effects we're looking for. This could apply to using too much Oil of Oregano.